性别：男
所在院系：
职称：研究员（三级）
导师类别：硕士生导师
政治面貌:中共党员
职务:中国水产科学研究院长江水产研究所所长、党委书记
Email:lcj@yfi.ac.cn
个人简介
李创举，1980年10月出生，理学博士，研究员，中国水产科学研究院长江水产研究所所长、党委书记，兼任农业农村部淡水生物多样性保护重点实验室主任、农业农村部淡水鱼类种质监督检验测试中心主任，博士生导师，从事鱼类遗传育种学方面的科研工作。研究领域包括鱼类遗传育种、鱼类基因组学及生长、生殖和代谢等重要生理活动的基因调控网络解析及应用、鱼类生殖细胞早期发育机理解析及生殖干细胞鉴定、分离、培养和保存等移植技术体系建立及应用等。主持或主持完成国家自然科学基金项目2项、国家重点研发计划项目课题1项及子课题2项、国家863项目子课题1项、其他省部级项目10余项；发表学术论文70余篇，授权国家发明专利5项。担任中国水产学会常务理事、全国水产标准化技术委员会淡水养殖分技术委员会主任委员。获2022—2023年度神农中华农业科技奖二等奖。
教育经历
200209 -200706，中国科学院水生生生物研究所，博士
199809-200206，陕西师范大学生物学专业，学士
工作经历
202401-至今中国水产科学研究院长江水产研究所,所长、党委书记
201801-202312 中国水产科学研究院长江水产研究所,副所长
201411-201511,重庆市水产科学研究所,副所长（挂职）
201211-201712,中国水产科学研究院长江水产研究所,研究室副主任
201701-至今 中国水产科学研究院长江水产研究所,研究员
201001-201612,中国水产科学研究院长江水产研究所,副研究员
200711-200912,中国水产科学研究院长江水产研究所,助理研究员
200707-200710,中国水产科学研究院长江水产研究所,见习
从事专业
鱼类遗传育种学
研究方向
1.淡水鱼类基因组学及遗传育种
2.淡水鱼类生殖细胞发育机制及移植
3.黄鳝繁育及营养调控
科研项目
1.2022年国家重点研发计划子课题“瓦氏黄颡鱼高效繁育及工程化养殖技术研发示范”（2022YFD2400902）
2.2018年国家重点研发计划“蓝色粮仓科技创新”子课题“施氏鲟生殖干细胞诱导与移植研究”（2018YFD0901205）
3.2015年国家自然科学基金面上项目“鲟鱼生殖细胞移植研究”（31472286）
4.2011年国家自然科学基金青年科学基金项目“中华鲟GnRH 和KiSS/GPR54 信号基因的克隆、表达及功能研究”（31001104）
5.2011年国家863项目子课题“多种淡水鱼类基因资源发掘与利用”（2011AA100401）
6.2020年农业农村部渔业渔政管理局项目“鄱阳湖、洞庭湖及汉江水域环境DNA调查”（17200493(CJ)-13）
7.2023年中国水产科学研究院创新团队“淡水鱼类生殖干细胞育种”（2023TD23）
8.2022年中国水产科学研究院基本业务费“鱼类生殖干细胞移植技术研究”（2022XT03）
9.2020年中国水产科学研究院长江水产研究所基本业务费“三种体色黄鳝生长发育的遗传基础”（2020JBF05）
10.2019年中国水产科学研究院基本业务费“三种体色黄鳝生长发育的遗传基础”（2019ZD0502）
11.2016年中国水产科学研究院基本业务费“鲟鱼不育受体制备及生殖细胞冷冻保存研究”（2016GH04）
12.2013年中国水产科学研究院基本业务费“中华鲟原始生殖细胞的鉴定、标记及追踪研究”（2013JBFZ01）
13.2021年杭州千岛湖驯龙科技股份有限公司技术服务项目“鲟鱼雌性性别特异性分子标记产业化应用”
14.2017年重庆市农业投资集团有限公司技术服务项目“异育银鲫新品种规模化繁育和养殖推广及岩原鲤种群遗传结构分析和核心育种材料创制关键技术研究”
代表性论文
1.Huang L#, Ye H#, Yue HM, Leng XQ, Ruan R, Du H,Li CJ*, Wu JM*. Comparative transcriptome analysis reveals sexually dimorphic gene expression in the gonads ofBrachymystax tsinlingensisLi. Animals, 2023, 13: 3690.
2.Ruan R, Li Y, Yue HM, Ye H, Jin JL, Wu JP, Du H*,Li CJ*. Transcriptome analyses reveal expression profiles of morphologically undifferentiated and differentiated gonads of Yangtze sturgeonAcipenser dabryanus. Genes, 2023, 14: 2058.
3.Deng HC, Yue HM*, Ruan R, Ye H, Li Z,Li CJ*. Dietary Epigallocatechin-3-Gallate (EGCG) improves nonspecific immune response of Chinese rice field eel (Monopterus albus). Aquaculture Nutrition, 2023: 6512136.
4.Ye H, Fan JH, Hou YL, Yue HM, Ruan R, Li S, Hu CJ, Xie Y*,Li CJ*. Chromosome-level genome assembly of the largefin longbarbel catfish (Hemibagrus macropterus). Frontiers in Genetics, 2023, 14:1297119.
5.Ye H#, Ruan R#, Song XH, Fan JH, Du H, Shao J, Wang YZ, Yue HM, Zhang T,Li CJ*. Identification of a candidate sex-determining gene, ptf1aY, in the Chinese longsnout catfish (Leiocassis longirostris) through high-throughput sequencing. Aquaculture reports, 2023, 32: 101730.
6.Jin JL, Chu ZP, Ruan R, Liu W, Chen XH*,Li CJ*. Phosphorus absorption and excretion in hybrid sturgeon (Huso dauricus♀ XAcipenser schrenckii♂) intubated with different Ca/P ratios. Fishes, 2022, 7, 138.
7.Yue HM, Ye H, Ruan R, Du H, Wei QW,Li CJ*. Intraperitoneal injection of 17β-estradiol increases ovarian smad2/3 expression in Yangtze sturgeonAcipenser dabryanus. Aquaculture Research, 2022, 53:3059–3068.
8.Yue HM, Wu JP, Fu P, Ruan R, Ye H, Hu B, Chen XH*,Li CJ*. Effect of glutamine supplementation against soybean meal-induced growth retardation, hepatic metabolomics and transcriptome alterations in hybrid sturgeonAcipenser baerii♀×A. schrenckii♂. Aquaculture Reports, 2022, 24:101158.
9.Ye H, Takeuchi Y, Du H, Yue HM, Ruan R,Li CJ*, Wei QW*. Spermatogonia from cryopreserved testes of critically endangered Chinese sturgeon efficiently colonized and preferentially proliferated in the recipient gonads of Yangtze sturgeon. Marine Biotechnology, 2022, 24, 136–150.
10.Ruan R, Feng T, Li Y, Yue HM, Ye H, Du H, Liu QY, Ruan J,Li CJ*, Wei QW*. Screening and identification of female-specific DNA sequences in octaploid sturgeon using comparative genomics with high-throughput sequencing. Genomics, 2021, 113(6): 4237–4244.
11.Chen M, Ruan R, Zhong XQ, Ye H, Yue HM, Li Z,Li CJ*. Comprehensive analysis of genome-wide DNA methylation and transcriptomics between ovary and testis inMonopterus albus. Aquaculture Research, 2021, 52(11): 5829-5839.
12.Yue HM, Fu P, Ruan R, Ye H, Li Z*,Li CJ*. Influence of broodstock diets on growth, fecundity and spawning performance of swamp eelMonopterus albus. Aquaculture Research, 2021, 52:1935–1944.
13.Yue HM, Huang XQ, Ruan R, Ye H, Li Z*,Li CJ*. Effect of dietary lipid on growth, body composition, serum biochemistry and hepatic metabolite alteration in Chinese rice field eel (Monopterus albus) fingerlings. Aquaculture Nutrition, 2021, 27:63–76.
14.Ye H, Zhou CL, Yue HM, Wu MB, Ruan R, Du H,Li CJ*, Wei QW*. Cryopreservation of germline stem cells in American paddlefish (Polyodon spathula). Animal Reproduction Science, 2021 (224):106667.
15.Ruan R, Chen M, Yue HM, Ye H,Li CJ*. Comparative transcriptome analysis of livers from three strains of Chinese swamp eels. Aquaculture Research, 2020, 51: 5251–5258.
16.Ye H, Takeuchi Y, Wu MB, Yue HM, Ruan R, Du H, Zhou CL, Hao Xiang H,Li CJ*, Wei QW*. Assessment of Yangtze sturgeon as recipient for the production of American paddlefish gametes through spermatogonia transplantation. Theriogenology, 2020, 158: 168e179.
17.Yue HM, Huang XQ, Ruan R, Ye H, Li Z*,Li CJ*. Effects of dietary protein levels on the growth, body composition, serum biochemistry and digestive enzyme activity in Chinese rice field eel (Monopterus albus) fingerlings. Aquaculture Research, 2020, 51: 400–409.
18.Yue HM, Ye H, Ruan R, Du H,Li CJ*, Wei QW*. Feedback regulation of 17β-estradiol on two kisspeptin genes in the Dabry's sturgeon (Acipenser dabryanus). Comparative Biochemistry and Physiology Part B, 2019, 230:1-9.
19.Ye H, Yue HM, Yang XG,Li CJ, Wei QW*. Molecular characterization, tissue distribution, localization and mRNA expression of the bucky ball gene in the Dabry's sturgeon (Acipenser dabryanus) during oogenesis. Gene Expression Patterns, 2018, 28: 62–71.
20.Ye H#,Li CJ#, Yue HM, Du H, Yang XG, Yoshino T, Hayashida T, Takeuchi Y*, Wei, QW*. Establishment of intraperitoneal germ cell transplantation for critically endangered Chinese sturgeon Acipenser sinensis. Theriogenology, 2017, 94:37-47.
21.Ye H, Yue HM, Yang XG,Li CJ*, Wei QW*. Identification and sexually dimorphic expression of vasa isoforms in Dabry’s sturgeon (Acipenser dabryanus), and functional analysis of vasa 3’-untranslated region. Cell & Tissue Research, 2016, 366 (1): 203-18.
22.Yue HM#,Li CJ#, Du H, Zhang SH, Wei QW*. Sequencing and De Novo assembly of the gonadal transcriptome of the endangered Chinese Sturgeon (Acipenser sinensis). Plos One, 2015, 10(6): e0127332.
23.Ye H#,Li CJ#, Yue HM, Yang XG, Wei QW*. Differential expression of fertility genes boule and dazl in Chinese Sturgeon (Acipenser sinensis), a basal fish. Cell & Tissue Research, 2015, 360 (2): 413-425.
24.Yang XG, Yue HM, Ye H,Li CJ*, Wei QW*. Identification of a germ cell marker gene, the dead end homologue, in Chinese sturgeonAcipenser sinensis. Gene, 2015,558 (1): 118-125.
25.Leng XQ,Li CJ*, Cao H*. Expression pattern of somatolactin in the Chinese sturgeon, Acipenser sinensis Gray, 1835. Journal of Applied Ichthyology, 2014, 30: 1222–1228.
26.Yue HM, Cao H, Chen XH, Ye H,Li CJ*, Du H*. Molecular characterization of the cDNAs of two zona pellucida genes in the Chinese sturgeon,Acipenser sinensisGray, 1835, Journal of Applied Ichthyology, 2014, 30: 1273-1281.
27.Yue HM, Ye H, Chen XH, Cao H,Li CJ*. Molecular cloning of cDNA of gonadotropin-releasing hormones in the Chinese sturgeon (Acipenser sinensis) and the effect of 17β-estradiol on gene expression. Comparative Biochemistry and Physiology Part A, 2013, 166: 529–537.
28.Ye H, Du H, Chen XH, Cao H, Liu T,Li CJ*. Identification of a pou2 ortholog in Chinese sturgeon,Acipenser sinensisand its expression patterns in tissues, immature individuals and during embryogenesis. Fish Physiology Biochemistry, 2012, 38(4): 929-942.
29.Ye H, Chen XH, Wei QW, Zhou L, Liu T, Gui JF,Li CJ*, Cao H*. Molecular and expression characterization of a nanos1 homologue in Chinese sturgeon,Acipenser sinensis. Gene, 511(2): 2012, 285-292.
30.Li CJ, Wei QW, Chen XH*, Zhou L, Cao H, Gan F, Gui JF. Molecular characterization and expression pattern of three zona pellucida 3 genes in the Chinese sturgeon,Acipenser sinensis. Fish Physiology Biochemistry, 2011, 37: 471–484.
31.Li CJ, Chen XH*, Zhang Y, Ye H, Liu T. Molecular and expression characterization of growth hormone/prolactin family genes in the Prenant's schizothoracin. Molecular Biology Reports, 2011, 38: 4595-4602.
32.Li CJ, Gan F, Chen XH*, Liu ZG, Li LX, Wei QW, Tang YK. Molecular and expression analysis of apolipoprotein E gene in the Chinese sturgeon,Acipenser sinensis. Comparative Biochemistry and Physiology Part B, 2011, 158: 64–70.
科技奖励
1. 鲟鱼新品种培育和产业化技术创新与应用.2022—2023年度神农中华农业科技奖二等奖（排3）
发明专利
1. 雌性施氏鲟特异性DNA片段及应用.专利号：ZL201910066534.7.
2.用于鲟鱼性别鉴定的特异性DNA片段SSM1及应用.专利号：ZL201910066600.0.
3.用于鲟鱼性别鉴定的特异性DNA片段SSM2及应用.专利号：ZL201910066586.4.
4.一种鲟鱼性腺组织的冷冻保存液和冷冻保存及复苏的方法.专利号：ZL202010440724.3.
5.一种长吻鮠雄性性别特异性分子标记及其扩增引物和遗传性别鉴定方法.专利号ZL202111232187.4.
学术专著
1. 参编《中华鲟保护生物学》（科学出版社，2019年6月）
